Table 1 Patients characteristics.
Variable | All patients (N = 365) | Ph-like ALL (N = 33) | Ph-pos ALL (N = 132) | Ph-neg ALL (N = 200) | p-Value |
|---|---|---|---|---|---|
Age at diagnosis (years) | 48 (17, 88) | 39 (17, 88) | 50 (21, 79) | 49 (17, 83) | 0.01 |
Age ≤ 40 years | 133 (36.3%) | 17 (51.5%) | 37 (28.0%) | 79 (39.5%) | 0.02 |
Sex (male) | 198 (54.2%) | 22 (66.7%) | 72 (54.5%) | 104 (52.0%) | 0.30 |
Race (Caucasian) | 311 (87.4%) | 28 (90.3%) | 113 (87.6%) | 170 (86.7%) | 0.91 |
Ethnicity (Hispanic/Latino) | 49 (14.6%) | 9 (28.1%) | 14 (11.7%) | 26 (14.1%) | 0.07 |
WBC | 9.0 (0.0, 700.0) | 27.9 (0.6, 199.0) | 21.5 (0.8, 571.0) | 4.5 (0.0, 700.0) | <0.001 |
Hb | 9.1 (0.0, 82.0) | 9.3 (6.1, 15.6) | 9.7 (4.0, 16.4) | 9.0 (0.0, 82.0) | 0.22 |
Platelets | 49 (0, 519) | 35 (3, 237) | 44 (2, 351) | 54 (0, 519) | 0.33 |
CNS involvement at diagnosis | 39 (10.7%) | 4 (12.1%) | 19 (14.4%) | 16 (8.0%) | 0.17 |
Induction regimen | 0.002 | ||||
Hyper CVAD | 238 (65.2%) | 16 (48.5%) | 99 (75.0%) | 123 (61.5%) | |
Pediatric regimens | 60 (16.4%) | 11 (33.3%) | 9 (6.8%) | 40 (20.0%) | |
ECOG regimens | 40 (11.0%) | 4 (12.1%) | 13 (9.8%) | 23 (11.5%) | |
Others | 27 (7.4%) | 2 (6.1%) | 11 (8.3%) | 14 (7.0%) | |
Allo-HCT | 253 (69.3%) | 18 (54.5%) | 109 (82.6%) | 126 (63.0%) | <0.001 |
