Table 2 Response and early mortality rates of newly diagnosed adults with AML.

From: Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements

Best Response

KMT2Ar

Age-matched diploid

P

N

172

522

 

CR

113 (66)

403 (77)

0.01

CRi

10 (6)

18 (4)

 

CR + CRi

123 (72)

421 (81)

 

No response

49 (28)

101 (19)

 

MRD negative by MFC (%)

17/25 (68)

90/132 (68)

0.9

Early mortality rates

30-day mortality

17 (10)

20 (4)

0.005

60-day mortality

26 (15)

38 (7)

0.004

  1. Values are n (%).
  2. CR complete remission, CRi complete remission with incomplete hematologic recovery, MRD measurable residual disease assessed by multiparameter flow cytometry (MFC) following induction in evaluable patients.