Fig. 2: Parallel plot demonstrating the change in the Mayo 2018 SMM risk score over time.

The colored lines represent patients based on their baseline SMM risk stratification, as shown in the legend. The line thickness is proportional to the number of patients within each SMM score stratum. At each annual time point post SMM diagnosis, the boxes represent the composition of patients re-categorized at high risk (red box), intermediate risk (green box), or low risk (blue box). This plot demonstrates that in some SMM patients, the risk categorization is dynamic over time.