Table 1 Patient demographic and transplant characteristics of the two cohorts.

From: A novel Iowa–Mayo validated composite risk assessment tool for allogeneic stem cell transplantation survival outcome prediction

 

Group

 

Covariate

Statistics

Level

UIHC N = 273

Mayo N = 348

P-value

Time Since Diagnosis

N (Col %)

6+ months

136 (49.8)

167 (48.0)

0.65

N (Col %)

<6 months

137 (50.2)

181 (52.0)

Age

N (Col %)

55+

144 (52.7)

193 (55.5)

0.50

N (Col %)

<55

129 (47.3)

155 (44.5)

Sex

N (Col %)

F

111 (40.7)

134 (38.5)

0.59

N (Col %)

M

162 (59.3)

214 (61.5)

Disease

N (Col %)

Acute lymphoblastic leukemia (ALL)

46 (16.8)

48 (13.8)

<0.01

N (Col %)

Acute myelogenous leukemia (AML)

119 (43.6)

172 (49.4)

N (Col %)

Myelodysplastic/myeloproliferative diseases (MDS/MPN)

60 (22.0)

80 (23.0)

N (Col %)

Non-Hodgkin lymphoma (NHL)

18 (6.6)

4 (1.1)

N (Col %)

Other

30 (11.0)

44 (12.6)

Performance Status at Transplant

N (Col %)

KPS 90+

178 (65.2)

214 (61.5)

0.34

N (Col %)

KPS < 90

95 (34.8)

134 (38.5)

Disease Risk Index

N (Col %)

High–Very High

97 (35.5)

71 (20.4)

<0.01

N (Col %)

Intermediate

116 (42.5)

189 (54.3)

N (Col %)

Low

60 (22.0)

88 (25.3)

Comorbidity Index

N (Col %)

High

192 (70.3)

94 (27.0)

<0.01

N (Col %)

Intermediate

56 (20.5)

165 (47.4)

N (Col %)

Low

25 (9.2)

89 (25.6)

Regimen

N (Col %)

Myeloablative

199 (72.9)

223 (64.1)

0.02

 

N (Col %)

RIC/Nonmyeloablative

74 (27.1)

125 (35.9)

 

Year of Transplant

N (Col %)

2010

40 (14.7)

36 (10.3)

<0.01

N (Col %)

2011

41 (15.0)

61 (17.5)

N (Col %)

2012

43 (15.8)

63 (18.1)

N (Col %)

2013

32 (11.7)

64 (18.4)

N (Col %)

2014

41 (15.0)

65 (18.7)

N (Col %)

2015

32 (11.7)

59 (17.0)

N (Col %)

2016

0 (0)

44 (16.1)

ABO

N (Col %)

A

113 (41.4)

140 (40.2)

0.99

N (Col %)

AB

11 (4.0)

15 (4.3)

N (Col %)

B

31 (11.4)

39 (11.2)

N (Col %)

O

118 (43.2)

154 (44.3)

CMV

N (Col %)

N

60 (22.0)

103 (29.6)

0.03

N (Col %)

P

213 (78.0)

245 (70.4)

Transplant Type

N (Col %)

Related

107 (39.2)

200 (57.5)

<0.01

N (Col %)

Unrelated

166 (60.8)

148 (42.5)

Match/Mismatch

N (Col %)

Match

229 (83.9)

335 (96.3)

<0.01

N (Col %)

Mismatch

44 (16.1)

13 (3.7)

Donor Age

N (Col %)

30+

140 (51.3)

250 (71.8)

<0.01

N (Col %)

<30

133 (48.7)

98 (28.2)

Donor Sex

N (Col %)

F

95 (34.8)

115 (33.0)

0.65

N (Col %)

M

178 (65.2)

233 (67.0)

Donor ABO/Rh

N (Col %)

A

111 (40.7)

136 (39.1)

0.19

N (Col %)

AB

14 (5.1)

15 (4.3)

N (Col %)

B

20 (7.3)

44 (12.6)

 

N (Col %)

O

128 (46.9)

153 (44.0)

 

Donor CMV

N (Col %)

N

178 (65.2)

187 (53.7)

<0.01

N (Col %)

P

95 (34.8)

161 (46.3)

  1. Where the p values indicate the differences in the characteristics between the two cohorts, and significant differences are noted as bold.