Table 1 Patient demographic and transplant characteristics of the two cohorts.
Group | |||||
---|---|---|---|---|---|
Covariate | Statistics | Level | UIHC N = 273 | Mayo N = 348 | P-value |
Time Since Diagnosis | N (Col %) | 6+ months | 136 (49.8) | 167 (48.0) | 0.65 |
N (Col %) | <6 months | 137 (50.2) | 181 (52.0) | ||
Age | N (Col %) | 55+ | 144 (52.7) | 193 (55.5) | 0.50 |
N (Col %) | <55 | 129 (47.3) | 155 (44.5) | ||
Sex | N (Col %) | F | 111 (40.7) | 134 (38.5) | 0.59 |
N (Col %) | M | 162 (59.3) | 214 (61.5) | ||
Disease | N (Col %) | Acute lymphoblastic leukemia (ALL) | 46 (16.8) | 48 (13.8) | <0.01 |
N (Col %) | Acute myelogenous leukemia (AML) | 119 (43.6) | 172 (49.4) | ||
N (Col %) | Myelodysplastic/myeloproliferative diseases (MDS/MPN) | 60 (22.0) | 80 (23.0) | ||
N (Col %) | Non-Hodgkin lymphoma (NHL) | 18 (6.6) | 4 (1.1) | ||
N (Col %) | Other | 30 (11.0) | 44 (12.6) | ||
Performance Status at Transplant | N (Col %) | KPS 90+ | 178 (65.2) | 214 (61.5) | 0.34 |
N (Col %) | KPS < 90 | 95 (34.8) | 134 (38.5) | ||
Disease Risk Index | N (Col %) | High–Very High | 97 (35.5) | 71 (20.4) | <0.01 |
N (Col %) | Intermediate | 116 (42.5) | 189 (54.3) | ||
N (Col %) | Low | 60 (22.0) | 88 (25.3) | ||
Comorbidity Index | N (Col %) | High | 192 (70.3) | 94 (27.0) | <0.01 |
N (Col %) | Intermediate | 56 (20.5) | 165 (47.4) | ||
N (Col %) | Low | 25 (9.2) | 89 (25.6) | ||
Regimen | N (Col %) | Myeloablative | 199 (72.9) | 223 (64.1) | 0.02 |
N (Col %) | RIC/Nonmyeloablative | 74 (27.1) | 125 (35.9) | ||
Year of Transplant | N (Col %) | 2010 | 40 (14.7) | 36 (10.3) | <0.01 |
N (Col %) | 2011 | 41 (15.0) | 61 (17.5) | ||
N (Col %) | 2012 | 43 (15.8) | 63 (18.1) | ||
N (Col %) | 2013 | 32 (11.7) | 64 (18.4) | ||
N (Col %) | 2014 | 41 (15.0) | 65 (18.7) | ||
N (Col %) | 2015 | 32 (11.7) | 59 (17.0) | ||
N (Col %) | 2016 | 0 (0) | 44 (16.1) | ||
ABO | N (Col %) | A | 113 (41.4) | 140 (40.2) | 0.99 |
N (Col %) | AB | 11 (4.0) | 15 (4.3) | ||
N (Col %) | B | 31 (11.4) | 39 (11.2) | ||
N (Col %) | O | 118 (43.2) | 154 (44.3) | ||
CMV | N (Col %) | N | 60 (22.0) | 103 (29.6) | 0.03 |
N (Col %) | P | 213 (78.0) | 245 (70.4) | ||
Transplant Type | N (Col %) | Related | 107 (39.2) | 200 (57.5) | <0.01 |
N (Col %) | Unrelated | 166 (60.8) | 148 (42.5) | ||
Match/Mismatch | N (Col %) | Match | 229 (83.9) | 335 (96.3) | <0.01 |
N (Col %) | Mismatch | 44 (16.1) | 13 (3.7) | ||
Donor Age | N (Col %) | 30+ | 140 (51.3) | 250 (71.8) | <0.01 |
N (Col %) | <30 | 133 (48.7) | 98 (28.2) | ||
Donor Sex | N (Col %) | F | 95 (34.8) | 115 (33.0) | 0.65 |
N (Col %) | M | 178 (65.2) | 233 (67.0) | ||
Donor ABO/Rh | N (Col %) | A | 111 (40.7) | 136 (39.1) | 0.19 |
N (Col %) | AB | 14 (5.1) | 15 (4.3) | ||
N (Col %) | B | 20 (7.3) | 44 (12.6) | ||
N (Col %) | O | 128 (46.9) | 153 (44.0) | ||
Donor CMV | N (Col %) | N | 178 (65.2) | 187 (53.7) | <0.01 |
N (Col %) | P | 95 (34.8) | 161 (46.3) |