Table 2 New risk stratification system including the number of focal lesions on PET/CT with the R-ISS.

From: Development of a new risk stratification system for patients with newly diagnosed multiple myeloma using R-ISS and 18F-FDG PET/CT

R-ISS/PET

R-ISS

No of FL

No (%)

OS at 2 years % (95% CI)

PFS at 2 years % (95% CI)

Stage I

I

≤ 3

31 (8.2)

96.7 (93.4–100.0)

84.1 (76.6–91.6)

Stage II

I

> 3

156 (41.1)

89.8 (86.9–92.7)

64.7 (60.0–69.4)

II

≤ 3

Stage III

II

> 3

162 (42.6)

74.7 (70.8–78.6)

40.8 (36.2–45.4)

III

≤ 3

Stage IV

III

> 3

31 (8.2)

50.3 (38.4–62.2)

17.1 (8.5–25.7)

  1. PET/CT positron emission tomography/computed tomography, R-ISS Revised International Staging System, R-ISS/PET Revised International Staging System/positron emission tomography, FL focal lesions, OS overall survival, PFS progression-free survival.