Fig. 6: Immune biomarkers of immunogenicity.

A Odds ratio univariate analysis with 95% confidence intervals (CI) of variables included in the logistic regression model. B Logistic regression coefficients with treatment-related features as well as immune biomarkers associated with generation of ≥553.5 IU/mL of IgG antibodies against the receptor-binding domain (RBD) of the S-glycoprotein. C Area under the curve (AUC) of prediction probabilities of patients’ dataset. D Correlation matrix of immune and treatment-related features. E Fourfold cross-validation of AUC of prediction probabilities of patients’ dataset.