Table 3 Association of incident NHL with incident breast cancer according to the time after diagnosis.

From: Risk of non-Hodgkin lymphoma in breast cancer survivors: a nationwide cohort study

Incidence of non-Hodgkin lymphoma

Non-Hodgkin lymphoma

DLBCL

Follicular lymphoma

Mature T/NK-cell lymphomas

ALCL

Other NHL*

No breast cancer

Reference

Reference

Reference

Reference

Reference

Reference

<1 year after diagnosis

HR (95% CI)

2.59 (1.79, 3.74)

2.36 (1.05, 5.29)

7.20 (2.63, 19.70)

3.62 (1.15, 11.40)

2.20 (1.34, 3.61)

P-value

<0.01

0.04

<0.01

0.03

<0.01

1 to < 3 years after diagnosis

HR (95% CI)

1.62 (1.13, 2.31)

0.68 (0.22, 2.12)

4.34 (1.59, 11.89)

3.52 (1.44, 8.63)

9.71 (2.22, 42.51)

1.53 (0.97, 2.41)

P-value

<0.01

0.51

<0.01

<0.01

<0.01

0.07

3 to < 5 years after diagnosis

HR (95% CI)

1.41 (0.91, 2.19)

1.19 (0.44, 3.19)

1.48 (0.20, 10.63)

1.90 (0.47, 7.70)

6.87 (0.91, 52.14)

1.43 (0.83, 2.47)

P-value

0.13

0.73

0.70

0.37

0.06

0.20

≥5 years after diagnosis

HR (95% CI)

1.29 (0.87, 1.91)

1.05 (0.43, 2.53)

2.12 (0.58, 8.66)

2.11 (0.67, 6.66)

10.73 (2.42, 47.56)

1.22 (0.73, 2.03)

P-value

0.21

0.92

0.30

0.20

<0.02

0.45

  1. ALCL anaplastic large cell lymphoma, DLBCL Diffuse large B-cell lymphoma, NHL non-Hodgkin lymphoma, HR hazard ratio, CI confidence interval, NHL non-Hodgkin lymphoma.
  2. Age as the time scale. Adjusted for body mass index categories (underweight, normal, overweight, obese, and unknown), alcohol consumption (none, moderate, heavy, and unknown), moderate–vigorous physical activity (none, 1–2 times per week, >3 times per week, and unknown), smoking status (never, ever, or unknown), and income percentile (Medicaid, ≤30th, 31st–70th, >70th).