Table 4 Association of incident NHL with incident breast cancer according to treatment status.
From: Risk of non-Hodgkin lymphoma in breast cancer survivors: a nationwide cohort study
Type of treatment after breast cancer | Non-Hodgkin lymphoma HR (95% CI) P-value | DLBCL HR (95% CI) P-value | Follicular lymphoma HR (95% CI) P-value | Mature T/NK-cell lymphomas HR (95% CI) P-value | ALCLHR (95% CI) P-value | Other NHL* HR (95% CI) P-value |
|---|---|---|---|---|---|---|
Any treatment | ||||||
Incident breast cancer without adjuvant therapy | Reference | Reference | Reference | Reference | Reference | Reference |
Incident breast cancer with adjuvant therapy | 0.77 (0.41, 1.43) 0.40 | 0.50 (0.15, 1.74) 0.28 | 0.37 (0.08, 1.71) 0.20 | – | – | 0.83 (0.36, 1.92) 0.66 |
Chemotherapy | ||||||
Incident breast cancer without chemotherapy | Reference | Reference | Reference | Reference | Reference | Reference |
Incident breast cancer with chemotherapy | 0.76 (0.51, 1.12) 0.16 | 0.59 (0.23, 1.48) 0.26 | 0.40 (0.12, 1.30) 0.13 | 1.09 (0.34, 3.57) 0.88 | 0.68 (0.11, 4.13) 0.67 | 0.83 (0.50, 1.39) 0.49 |
Radiation therapy | ||||||
Incident breast cancer without radiation therapy | Reference | Reference | Reference | Reference | Reference | Reference |
Incident breast cancer with radiation therapy | 0.95 (0.61, 1.48) 0.81 | 1.17 (0.39, 3.56) 0.78 | 0.78 (0.21, 2.96) 0.72 | 0.98 (0.27, 3.58) 0.98 | 0.42 (0.07, 2.51) 0.34 | 0.90 (0.51, 1.59) 0.72 |
Hormone therapy | ||||||
Incident breast cancer without hormone therapy | Reference | Reference | Reference | Reference | Reference | Reference |
Incident breast cancer with hormone therapy | 2.68 (1.83, 3.94) < 0.01 | 2.15 (0.83, 5.55) 0.11 | 1.26 (0.33, 4.75) 0.73 | 3.91 (1.31, 11.64) 0.01 | 4.81 (0.80, 28.89) 0.09 | 2.98 (1.82, 4.89) < 0.01 |
