Table 1 Patients characteristics and anti-SARS-CoV-2 seroconversion rate.

From: Patterns of neutralizing humoral response to SARS-CoV-2 infection among hematologic malignancy patients reveal a robust immune response in anti-cancer therapy-naive patients

 

No (%)

Characteristic

Patients

(n = 189)

Seropositive

(n = 162)

Seronegative

(n = 27)

p-value

Age, median (range) years

62.6 (21-87)

62.7 (21-85)

59.8 (33-87)

0.74

Gender

   

1.00

 Male

119 (63.0)

102 (85.7)

17 (14.3)

 

 Female

70 (37.0)

60 (85.7)

10 (14.3)

 

Presence of comorbidities (≥1)

87 (46.0)

73 (83.9)

14 (16.1)

0.51

Cancer diagnosis

   

0.26

 Lymphoid malignancies

92 (48.7)

75 (81.5)

17 (18.5)

 

 Myeloid neoplasms

53 (28.0)

48 (90.6)

5 (9.4)

 

 Plasma cell disorders

44 (23.3)

39 (88.6)

5 (11.4)

 

Cancer status during SARS-CoV-2 infection

   

0.01

 Watch and wait

37 (19.6)

35 (94.6)

2 (5.4)

 

 Stable/Progressive disease

33 (17.5)

23 (69.7)

10 (30.3)

 

 Complete/Partial response

117 (61.9)

102 (87.2)

15 (12.8)

 

Active anti-cancer treatment during SARS-CoV-2 infection

71 (37.6)

57 (80.3)

14 (19.7)

0.11

Chemotherapy-based treatment during SARS-CoV-2 infection

27 (38.0)

20 (74.1)

7 (25.9)

0.30

Chemotherapy-free treatment during SARS-CoV-2 infection

44 (62.0)

37 (84.1)

7 (15.9)

 

Severe/ Critical COVID-19

45 (23.8)

42 (93.3)

3 (6.7)

0.11

Time from first SARS-CoV-2-positive test to antibody testing ≤ 6 months

152 (80.4)

131 (86.2)

21 (13.8)

0.71

Time from first SARS-CoV-2-positive test to antibody testing > 6 months

37 (19.6)

31 (83.8)

6 (16.2)