Fig. 5: Bone marrow T cell receptor beta (TRB) cluster analysis using the GLIPH2 algorithm. | Blood Cancer Journal

Fig. 5: Bone marrow T cell receptor beta (TRB) cluster analysis using the GLIPH2 algorithm.

From: Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients

Fig. 5

Applying the GLIPH2 algorithm we identified TRB clusters sharing antigen specificity with relevant overlap between healthy donors (HD) and AML samples (A). Thereby, B displays exemplary clonal space analysis for four AML patients pre- and post-azacitidine and the contribution of AML specific clusters as well as clusters shared with HD.

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