Table 1 Baseline characteristics of patients with grade 1–3 A, stage I–II follicular lymphoma managed at MSK between 1998 and 2009.

From: Clinical outcomes with use of radiation therapy and risk of transformation in early-stage follicular lymphoma

 

All patients

Completely stageda

 

(N = 295)

(N = 154)

 

Characteristic

No.

%

No.

%

P

Age: Median (IQR)

58 (48–67)

57 (47–65)

0.25

  

Sex

 Female

156

53

78

51

0.69

 Male

139

47

76

49

 

Stage

 I

172

58

94

61

0.61

 II

123

42

60

39

 

Grade

 1–2

227

86

121

83

0.39

 3 A

36

14

25

17

 

 Unknown

32

8

   

FLIPI

 Low

209

87

117

89

0.74

 Intermediate-High

30

13

14

11

 

 Unknown

56

23

   

LDH

 Elevated

25

12

13

11

0.86

 Normal

189

88

108

89

 

 Unknown

81

33

   

Hemoglobin

 Decreased

15

6

7

5

1.00

 Normal

244

94

130

95

 

 Unknown

36

17

   

Nodal areas

 >4

8

3

3

2

0.76

 ≤4

287

97

151

98

 

Bulky disease (>7 cm)

 Yes

30

16

14

12

0.50

 No

160

84

100

88

 

 Unknown

105

40

   

PET staged

 Yes

206

70

154

100

NA

 No

89

30

0

0

 

SUVmax

 >12

13

10

9

9

1.00

 ≤12

123

90

90

91

 

 Unknown

159

55

   

Bone marrow negativity

 Yes

220

75

154

100

NA

 Unknown

75

25

0

0

 

Initial management

 Initial observation

137

46

55

36

0.03

 Immediate treatment

158

54

99

64

 
  1. aCompletely staged patients underwent PET scan and bone marrow biopsy at diagnosis.
  2. IQR interquartile range, FLIPI Follicular Lymphoma International Prognostic Index, LDH lactate dehydrogenase, PET positron emission tomography, SUV standard uptake value.
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