Table 3 Survival analysis in all eligible patients with stage I–II follicular lymphoma based on management approach.

From: Clinical outcomes with use of radiation therapy and risk of transformation in early-stage follicular lymphoma

  

Initial observation

Combined modality treatment

Radiation therapy alone

Systemic treatment

  

(N = 137)

(N = 21)

(N = 108)

(N = 29)

OS since diagnosis

5-year (95% CI)

94.6% (0.907–0.986)

100.0% (1.000–1.000)

98.0% (0.953–1.000)

82.6% (0.699–0.977)

HRa (95% CI)

1.30 (0.60–2.81), p = 0.51

NA, p = 1.00

Reference

3.38 (1.29–8.86), p = 0.01

PFS since treatment

5-year (95% CI)

78.9% (0.626–0.996)

62.3% (0.537–0.723)

45.7% (0.304–0.689)

HRa (95% CI)

0.36 (0.14–0.90), p = 0.03

Reference

1.53 (0.88–2.65), p = 0.13

  1. aHazard ratio and corresponding p-value was adjusted for the Follicular Lymphoma International Prognostic Index (FLIPI). OS overall survival, HR hazard ratio, Inf infinity, PFS progression-free survival.