Table 1 Patient baseline demographics and characteristics.
|  | First line (n = 6137) | Second line (n = 3160) | Third line (n = 1654) |
|---|---|---|---|
Sex, n (%) | |||
 Female | 2752 (44.8) | 1438 (45.5) | 769 (46.5) |
 Male | 3385 (55.2) | 1722 (54.5) | 885 (53.5) |
Race, n (%) | |||
 White | 3804 (62.0) | 2018 (63.9) | 1069 (64.6) |
 African American | 982 (16.0) | 518 (16.4) | 276 (16.7) |
 Asian | 110 (1.8) | 60 (1.9) | 27 (1.6) |
 Hispanic/Latino | 60 (1.0) | 36 (1.1) | 16 (1.0) |
 Other | 721 (11.7) | 350 (11.1) | 182 (11.0) |
 Missing | 460 (7.5) | 178 (5.6) | 84 (5.1) |
 Median age at diagnosis, years [Q1, Q3] | 69.0 [61.0, 76.0] | 68.0 [60.0, 76.0] | 67.0 [59.0, 74.0] |
Practice type, n (%) | |||
 Academic | 680 (11.1) | 395 (12.5) | 223 (13.5) |
 Community | 5457 (88.9) | 2765 (87.5) | 1431 (86.5) |
 Median follow-up time, months [Q1, Q3] | 22.3 [8.85, 43.8] | 18.2 [6.91, 35.9] | 14.7 [5.67, 30.3] |
ECOG PS, n (%) | |||
 0 | 1222 (19.9) | 692 (21.9) | 379 (22.9) |
 1 | 1248 (20.3) | 974 (30.8) | 578 (34.9) |
 2 | 485 (7.9) | 369 (11.7) | 226 (13.7) |
 3+ | 168 (2.7) | 95 (3.0) | 51 (3.1) |
 Missing | 3014 (49.1) | 1030 (32.6) | 420 (25.4) |
ISS stage at diagnosis, n (%) | |||
 Stage I | 1152 (18.8) | 578 (18.3) | 302 (18.3) |
 Stage II | 1208 (19.7) | 638 (20.2) | 342 (20.7) |
 Stage III | 1254 (20.4) | 686 (21.7) | 368 (22.2) |
 Unknown/not documented | 2523 (41.1) | 1258 (39.8) | 642 (38.8) |
Prior malignancya, n (%) | |||
 Yes | 594 (9.7) | 310 (9.8) | 159 (9.6) |
 No | 5543 (90.3) | 2850 (90.2) | 1495 (90.4) |
Received maintenanceb therapy, n (%) | |||
 No | 4854 (79.1) | 2836 (89.7) | 1569 (94.9) |
 Yes | 777 (12.7) | 155 (4.9) | 21 (1.3) |
 Missing | 506 (8.2) | 169 (5.3) | 64 (3.9) |
Cytogenetics test, n (%) | |||
 Results unknown/not documented | 36 (0.6) | 16 (0.5) | 10 (0.6) |
 Yes | 4614 (75.2) | 2642 (83.6) | 1422 (86.0) |
 No | 1487 (24.2) | 502 (15.9) | 222 (13.4) |
Cytogenetic test type, n (%) | |||
 Both FISH & karyotype | 3295 (53.7) | 1998 (63.2) | 1135 (68.6) |
 FISH only | 829 (13.5) | 375 (11.9) | 161 (9.7) |
 Karyotype only | 526 (8.6) | 285 (9.0) | 136 (8.2) |
 Missing | 1487 (24.2) | 502 (15.9) | 222 (13.4) |
FISH cytogenetic abnormality, n (%) | |||
 No abnormalities identified | 1478 (24.1) | 878 (27.8) | 453 (27.4) |
 Present | 3172 (51.7) | 1780 (56.3) | 979 (59.2) |
 Missing | 1487 (24.2) | 502 (15.9) | 222 (13.4) |
