Table 1 Definition of response criteria.

From: Long-term follow-up of cladribine treatment in hairy cell leukemia: 30-year experience in a multicentric Italian study

CR

Recovery of hemoglobin above 11 g/dl, platelets above 100 × 109/l, ANC above 1.5 × 109/l

Normal spleen diameter by physical exam

No evidence of disease both in peripheral blood and bone marrow by non-immunological stains

PR

Recovery of peripheral blood count as for CR

At least 50% reduction of splenomegaly

At least 50% reduction of bone marrow infiltration by morphology

HR

Improvement by 50% of peripheral blood counts

NR

No improvement in peripheral blood count

No reduction of splenomegaly

No reduction of bone marrow infiltration