Table 1 Definition of response criteria.
CR | Recovery of hemoglobin above 11 g/dl, platelets above 100 × 109/l, ANC above 1.5 × 109/l |
Normal spleen diameter by physical exam | |
No evidence of disease both in peripheral blood and bone marrow by non-immunological stains | |
PR | Recovery of peripheral blood count as for CR |
At least 50% reduction of splenomegaly | |
At least 50% reduction of bone marrow infiltration by morphology | |
HR | Improvement by 50% of peripheral blood counts |
NR | No improvement in peripheral blood count |
No reduction of splenomegaly | |
No reduction of bone marrow infiltration |