Table 2 Median (IQR) levels of serum kappa and lambda FLC and FLC ratio in subgroups according to age, sex, and categories of reduced estimated glomerular filtration rate.

From: Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: Results of the iStopMM study

 

Kappa (mg/L)

Lambda (mg/L)

FLC ratio

Age (years)

 < 50

16.2 (13.6–25.5)

16.6 (12.7–23.0)

1.05 (0.87–1.28)

 50–59

17.9 (13.5–25.1)

16.2 (12.8–22.9)

1.10 (0.91–1.30)

 60–69

19.1 (14.9–24.9)

17.7 (14.0–22.7)

1.09 (0.91–1.29)

 70–79

21.7 (16.9–28.8)

18.8 (15.0–24.6)

1.16 (0.97–1.39)

 ≥ 80

24.8 (19.1–33.9)

20.8 (16.2–26.8)

1.23 (1.02–1.46)

Sex

 Male

23.1 (17.6–32.0)

19.8 (15.3–26.1)

1.19 (0.98–1.42)

 Female

20.4 (15.9–27.4)

18.2 (14.5–23.8)

1.13 (0.95–1.36)

eGFR (mL/min/1.73 m2)

 45–59

19.5 (15.5–25.2)

17.5 (14.0–22.1)

1.13 (0.94–1.35)

 30–44

27.2 (20.8–36.4)

22.6 (17.8–29.1)

1.21 (1.01–1.45)

 15–29

39.1 (30.2–54.8)

30.8 (23.4–40.5)

1.31 (1.12–1.57)

 < 15

71.5 (54.0–84.1)

49.1 (38.9–77.5)

1.33 (1.03–1.59)

  1. eGFR Estimated glomerular filtration rate, FLC Free light chain.
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