Fig. 1: HMMR splice variant transcripts are frequently expressed in MM patients. | Blood Cancer Journal

Fig. 1: HMMR splice variant transcripts are frequently expressed in MM patients.

From: Identification of disease-related aberrantly spliced transcripts in myeloma and strategies to target these alterations by RNA-based therapeutics

Fig. 1

A, B HMMR transcript expression was evaluated by RT-PCR followed by DNA fragment analyses and capillary electrophoresis. On the figures, the y axes display relative fluorescent units (RFU) of the PCR products. PCR product RFU = lg(RFU). RFU is a unit of measurement calculated relative to the size standards included in each reaction and compared to HMMR expression values detected in healthy donor BM PCs. In panel A, the x axes display patient samples, while in (B) the x axes display splice variants of HMMR. A displays splice variant co-expressions within individual patient samples (each bar represents one patient sample). B displays individual HMMR splice variant expression levels in MM patient samples.

Back to article page