Fig. 2: Illustrative histopathologic and laboratory findings in renal TMA. | Blood Cancer Journal

Fig. 2: Illustrative histopathologic and laboratory findings in renal TMA.

From: Mutations in the alternative complement pathway in multiple myeloma patients with carfilzomib-induced thrombotic microangiopathy

Fig. 2

A Hematoxylin and eosin stain of a kidney biopsy obtained from TMA patient #10. Image shows extensive cortical necrosis, with recent thrombosis of a small interlobular artery (A), thrombosis of glomerular capillaries (G), congestion of peritubular capillaries and focal interstitial hemorrhage (arrows), and widespread tubular necrosis (t) and coagulative necrosis of all elements within the kidney cortex. B Trend of creatinine and platelet count for TMA patient #10. Days indicate hospital days, following TMA development.

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