Table 1 Analytical and operational differences between the screening PCPRO and NGF MRD tests.

From: Utility of flow cytometry screening before MRD testing in multiple myeloma

 

PCPRO

NGF MRD

Target event collection

5 × 105

1 × 107

Maximum sensitivity

4 × 10−5

2 × 10−6

Observed median sensitivity

4.4 × 10−5

2.4 × 10−6

Amount of antibody needed

Low

High

Instrument time per patient

6 min

16 min

Analysis time per patient

5 min

20 min

Gating skills needed

Moderate

High

PC S-phase assessment

Yes

No

Hemodilution assessment

No

Yes

Immune microenvironment assessment

No

Partial