Fig. 1: DDX41-positive donor cell leukemia. | Blood Cancer Journal

Fig. 1: DDX41-positive donor cell leukemia.

From: DDX41 germline variants causing donor cell leukemia indicate a need for further genetic workup in the context of hematopoietic stem cell transplantation

Fig. 1

A Timeline of disease course of the reported male patient with donor cell leukemia (DCL). B Pedigree of the family of our patient with DCL. C Detected germline and somatic variants in DDX41 as well as DNMT3A mutational status after diagnosis of DCL of our case and reported cases of DDX41-associated DCL from the literature. *Stated as p.F498fs in the original article. AML acute myeloid leukemia, BM bone marrow, BW body weight, DCL donor cell leukemia, DCMDS donor cell myelodysplastic syndrome, HSCT hematopoietic stem cell transplantation, MDS myelodysplastic syndrome, VAF variant allel frequency, DDX41 NM_016222.4, DNMT3A NM_022552.5.

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