Table 1 Subject co-variates (N – 68).
From: Cell-free DNA chromosome copy number variations predict outcomes in plasma cell myeloma
N | ||
|---|---|---|
Male | 35 | |
Age at diagnosis (years) | Median (range) | 59 (34–74) |
<65 | 49 | |
≥65 | 19 | |
D–S stage | I | 0 |
II | 3 | |
III | 65 | |
ISS stage | I | 18 |
II | 36 | |
III | 14 | |
R-ISS stage | I | 12 |
II | 52 | |
III | 4 | |
Extra-medullary plasmacytoma | 18 | |
BM plasma cells (%) | ≥50 | 17 |
Hemoglobin (g/L) | <100 | 27 |
Platelets (10E + 9/L) | <100 | 2 |
Serum LDH (U/L) | ≥245 | 17 |
Serum creatinine (mg/dL) | ≥2 | 7 |
Serum calcium (mmol/L) | ≥2.65 | 12 |
ALB level (mg/dL) | <35 | 27 |
β2M (mmol/L) | ≥3.5 | 37 |
M-protein | IgG | 23 |
IgM | 0 | |
IgA | 19 | |
IgD | 5 | |
Light-chain | 17 | |
Non-secretory | 4 | |
Light-chain | Kappa | 38 |
Lambda | 26 | |
Non-secretory | 4 | |
sFLCR | 0.01–100 | 33 |
≤0.01, ≥100 | 35 | |
del(13q) | 17 | |
del(17p) | 3 | |
1q21 gain | 28 | |
t(4;14) | 13 | |
t(11;14) | 5 | |
t(14;16) | 0 | |
Double hit | 5 | |
Triple hit | 1 |
