Fig. 2: Analysis of serum samples. | Blood Cancer Journal

Fig. 2: Analysis of serum samples.

From: Proteomics uncovers molecular features for relapse risk stratification in patients with diffuse large B-cell lymphoma

Fig. 2

A Volcano plot showing 298 proteins identified in at least 70% of serum samples in each response group. 20 of these proteins were differentially expressed between relapsing and treatment-sensitive samples. Red, upregulated; green, downregulated (p < 0.05). B 3D PCA of 12 differentially expressed serum proteins that were present in all samples. C Dendrogram showing hierarchical clustering of samples based on 20 differentially expressed serum proteins. Black lines, treatment-sensitive lymphomas; pink lines, relapsing lymphomas. D Boxplot of 20 differentially expressed proteins in serum samples from relapsing and treatment-sensitive patients. Proteins are referred to by their gene names for simplicity. R relapsing lymphomas; S treatment-sensitive lymphomas.

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