Fig. 3: Hierarchical clustering using Ollivier Ricci Curvature (ORC) predicts progression-free survival (PFS) in multiple myeloma. | Blood Cancer Journal

Fig. 3: Hierarchical clustering using Ollivier Ricci Curvature (ORC) predicts progression-free survival (PFS) in multiple myeloma.

From: Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival

Fig. 3

Kaplan–Meier analysis of PFS based on ORC according to (A) copy number aberration, and (B) RNA sequencing. To better understand the differences between the high risk and low risk cohorts, clusters with similar outcomes were grouped. C For CNA based clustering, clusters 1–6 and 8 were combined into the low-risk group. Cluster 7 was the high-risk group. D For RNA-sequencing data, clusters 4 and 6 were combined into a high-risk group. Clusters 1 and 3 were combined into a low-risk group.

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