Fig. 4: Local neighborhood of selected genes relevant to MM biology and the immune system. | Blood Cancer Journal

Fig. 4: Local neighborhood of selected genes relevant to MM biology and the immune system.

From: Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival

Fig. 4

Each line or edge represents the interaction between a gene-pair in a network, comparing the median interactions observed in the high-risk group compared with those in the low-risk group. Blue edges indicate that the connections are more robust in the high-risk group, while orange edges are more fragile, risk being defined by the RNA-Seq-based clustering analysis. A: TP53, B: ATM, C: CCND1, D: MYC, E: IL6, F: IFNGR1, G: TNFRSF17, H: CD38, I: IKZF3. Higher resolution images are available at www.github.com/aksimhal/mm-orc-subtypes.

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