Table 2 Gene expression in 8 novel immune-network genes associate with survival.

From: Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival

Gene

Coefficient

95%–105% Range

Q-value

Gene description

Number of ImmunoSigDB gene sets

BUB1

1.36 ± 0.05

1.22–1.51

1.71e-8

BUB1 mitotic checkpoint serine/threonine kinase

5

MCM6

1.45 ± 0.07

1.27–1.66

6.19e-8

Minichromosome maintenance complex component 6

4

NOSTRIN

1.58 ± 0.11

1.27–1.98

4.49e-5

Nitric oxide synthase trafficking

1

PAM

0.72 ± 0.08

0.62–0.83

1.34e-5

Peptidylglycine alpha-amidating monooxygenase

7

RNF115

1.42 ± 0.11

1.14–1.77

1.72e-3

Ring finger protein 115

6

SNCAIP

1.40 ± 0.09

1.17–1.67

2.03e-4

Synuclein alpha interacting protein

1

SPRR2A

1.34 ± 0.05

1.22–1.46

1.43e-10

Small proline rich protein 2 A

3

WEE1

1.32 ± 0.04

1.23–1.41

6.19e-15

WEE1 G2 checkpoint kinase

9

  1. Coefficients <1 indicate a protective effect—associated with longer PFS. Coefficients >1 indicate a detrimental effect—associated with a shorter PFS.
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