Table 1 Characteristics of BM aspirated samples.

From: Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometry: Proposal for a bone marrow quality index

Characteristic

All samples (n = 351)

MGUS (n = 128)

SMM (n = 186)

MM (n = 37)

age, median (range)

69 (43–89)

69 (43–88)

68 (44–88)

70 (49–89)

sex (%)

63% M - 37% F

43% M - 57% F

64% M - 36% F

78% M - 22% F

Type, no. (%)

 IgG

167 (47.6%)

68 (53.1%)

81 (43.5%)

18 (48.6%)

 IgA

94 (26.8%)

30 (23.4%)

58 (31.2%)

6 (16.2%)

 biclonal

30 (8.5%)

12 (9.4%)

15 (8.1%)

3 (8.1%)

 light-chaina

60 (17.1%)

18 (14.1%)

32 (17.2%)

10 (27.0%)

M-proteinb (g/dL), median (IQR)

5.0 (1.0-11.0)

1.0 (0.2-3.0)

7.3 (4.0-13.0)

16.2 (8.0-53.0)

FLC ratioc, median (IQR)

15.6 (5.3-53.1)

3.2 (2.1-4.6)

19.1 (12.0-41.3)

183 (131-321)

BMPCd (%), median (IQR)

13% (8%-26%)

8% (3%-8%)

18% (16%-26%)

51% (33%-66%)

BM sample pull, no (%)

 first

219 (62.4%)

44 (34.4%)

143 (76.9%)

32 (86.5%)

 second

132 (37.6%)

84 (65.6%)

43 (23.1%)

5 (13.5%)

  1. MGUS monoclonal gammopathy of undetermined significance, SMM smoldering multiple myeloma, MM multiple myeloma, Ig immunoglobulin, BM bone marrow, M monoclonal, FLC free light-chain, BMPC bone marrow plasma cells, IQR Interquartile range. aLight-chain monoclonal gammopathy (abnormal light-chain levels and no detected M-protein); btotal serum M-protein concentration for individuals with identified M-protein; cFLC ratio (involved/uninvolved) for individuals with light-chain monoclonal gammopathy; dBMPC count by aspirate and biopsy with the higher value used (available for 336/351 samples).
Back to article page