Fig. 2: Expressionof G protein–coupled receptor class C group 5 member D (GPRC5D) in healthy tissues and in multiplemyeloma (MM) versus other cancer types.
From: GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review
The first panel (A) shows mRNA expression levels of GPRC5D across a range of healthy tissues. The second panel (B) shows mRNA expression levels of GPRC5D in multiple myeloma compared with expression levels observed across a range of hematological and solid tumor malignancies. ALL acute lymphoblastic leukemia, AML acute myeloid leukemia, CML chronic myelogenous leukemia, DLBCL diffuse large B- cellly mphoma, NSC non-small cell. Reproduced from Smith EL, et al. GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells. Sci Transl Med. 2019;11(485):eaau7746.
