Fig. 3: Structure of bispecific antibodies and GPRC5D-targeting CAR-T therapies.
From: GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review
The first panel (A) shows a generalized structure ofGPRC5D-targeting bispecific antibodies with the Fc region and CD3 and antigen-binding regions depicted. The second panel (B) shows the structure of CAR-T therapies with the target scFv and spacer regions and costimulatory and CD3 signaling domains depicted.
