Table 1 Specimens and diagnoses.

From: Dual T-cell constant β chain (TRBC)1 and TRBC2 staining for the identification of T-cell neoplasms by flow cytometry

Cohort

Diagnoses (n)

Specimens/patients

Specimen type (n)

Panels (**) (n)

Healthy donors

N/A

39 / 39

Peripheral blood (39)

T-cell (25)

Sezary (21)

Vβ/TRBC (5)

Naïve/memory (10)

Clinical specimens with no

T-cell malignancy

B-cell neoplasm (22)

Inflammatory/autoimmune (25)

Plasma cell proliferative disorder (13)

Thymic epithelial neoplasia (9)

Reactive cytopenia or cytosis (8)

Carcinoma (8)

Benign effusion (7)

Myeloid neoplasm (7)

Infectious (4)

Benign thymic tissue (1)

104 / 102

Bone marrow (34)

Lymph node / tissue (41)

Peripheral blood (16)

Body fluids (13)

T-cell (103)

Sezary (11)

T-cell neoplasms

Cutaneous T-cell lymphoma (23)

T lymphoblastic leukemia/lymphoma (11)

T-cell large granular lymphocytic leukemia (9)(*)

Peripheral T-cell lymphoma (12)(*)

T-cell prolymphocytic leukemia (3)

Lymphocytic variant hypereosinophilic syndrome (3)

Hepatosplenic T-cell lymphoma (1)

60 / 57

Peripheral blood (38)

Bone marrow (13)

Lymph node / tissue (9)

T-cell (46)

Sezary (18)

  1. (*) Two samples from one patient had both peripheral T-cell lymphoma and T-cell large granular lymphocytic leukemia.
  2. (**) Same samples were studied with more than one panel.
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