Fig. 2: Dynamics of FLT3 clones and protein simulation. | Blood Cancer Journal

Fig. 2: Dynamics of FLT3 clones and protein simulation.

From: Non-canonical FLT3 alterations reveal novel germline FLT3 variants leading to somatic gene rescue mutations

Fig. 2

A Gene structure depicting the location of the three germline FLT3 variants. B Bar graph showing the frequency of each variant in the general population versus disease population at our institution. C In silico prediction of three germline FLT3 variants. Simulated using Glide from Schrodinger Inc. and visualized with PyMOL. D Clonal dynamics and example of somatic genetic rescue.

Back to article page