Table 1 Baseline patients’ and transplant characteristics.
Characteristics | All n = 252 (%) | BuFlu n = 127 (%) | BuCy2 n = 125 (%) | p |
|---|---|---|---|---|
Age, years | ||||
Median (range) | 50.8 (38–65) | 51.1 (38–65) | 50.5 (39–65) | ns |
<51 | 128 (50.8) | 62 (48.8) | 66 (52.8) | ns |
≥51 | 124 (49.2) | 65 (51.2) | 59 (47.2) | ns |
Sex | ||||
Female | 113 (44.8) | 57 (44.9) | 56 (44.8) | ns |
Male | 139 (55.2) | 70 (55.1) | 69 (55.2) | ns |
AML type | ||||
De novo | 205 (81.3) | 103 (81.1) | 102 (81.6) | ns |
Secondary | 46 (18.3) | 24 (18.9) | 22 (17.6) | ns |
Unknown | 1 (0.4) | 0 | 1 (0.8) | ns |
Disease status at alloSCT | ||||
1° CR | 213 (84.5) | 108 (85.0) | 105 (84) | ns |
≥2° CR | 37 (14.7) | 18 (14.2) | 19 (15.2) | ns |
Unknown | 2 (0.8) | 1 (0.8) | 1 (0.8) | ns |
ELN risk | ||||
Good | 27 (10.7) | 13 (10.2) | 14 (11.2) | ns |
Intermediate-1 | 123 (48.8) | 62 (48.8) | 61 (48.8) | ns |
Intermediate-2 | 40 (15.9) | 17 (13.4) | 23 (18.4) | ns |
Adverse | 55 (21.8) | 32 (25.2) | 23 (18.4) | ns |
Unknown | 7 (2.8) | 3 (2.4) | 4 (3.2) | ns |
Donor type | ||||
Related | 114 (45.2) | 58 (45.7) | 56 (44.8) | ns |
Unrelated | 138 (54.8) | 69 (54.3) | 69 (55.2) | ns |
Graft source | ||||
Bone marrow | 77 (30.6) | 36 (28.3) | 41 (32.8) | ns |
Peripheral blood | 168 (66.7) | 88 (69.3) | 80 (64.0) | ns |
Unknown | 7 (2.8) | 3 (2.4) | 4 (3.2) | ns |
Donor-recipient sex pair | ||||
Female to male | 42 (16.7) | 23 (18.1) | 19 (15.2) | ns |
Others | 209 (82.9) | 104 (81.9) | 105 (84.0) | ns |
Unknown | 1 (0.4) | 0 | 1 (0.8) | ns |
Recipient/donor CMV serology | ||||
Negative/negative | 20 (8.0) | 12 (9.5) | 8 (6.4) | ns |
Negative/positive | 16 (6.3) | 6 (4.7) | 10 (8.0) | ns |
Positive/negative | 68 (27.0) | 37 (29.1) | 31 (24.8) | ns |
Positive /positive | 144 (57.1) | 69 (54.3) | 75 (60.0) | ns |
Unknown | 4 (1.6) | 3 (2.4) | 1 (0.8) | ns |
