Fig. 2: Transcriptional cluster was independently associated with DFS of t(8;21) AML. | Blood Cancer Journal

Fig. 2: Transcriptional cluster was independently associated with DFS of t(8;21) AML.

From: Multiomic analysis identifies a high-risk subgroup that predicts poor prognosis in t(8;21) acute myeloid leukemia

Fig. 2

A Forest plot for univariate Cox regression analysis of factors impacting DFS-HSCT. DFS-HSCT: disease-free survival censored at transplantation. B Forest plot for univariate Cox regression analysis of factors impacting DFS. C Forest plots for multivariate Cox regression analysis of factors impacting DFS-HSCT and DFS. Variables that entered into the multivariate Cox model for DFS-HSCT and DFS initially included WBC counts, FLT3-ITD alterations, MFC-MRD, and transcriptional clusters. WBC: white blood cells. MFC-MRD: measurable residual disease levels evaluated by multiparameter flow cytometry. D DFS-HSCT of t(8;21) AML patients classified as Cluster 1 and non-Cluster 1 (upper) and DFS of t(8;21) AML patients classified as Cluster 1 and non-Cluster 1 (lower).

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