Fig. 2: DEK expression is associated with cell lines derived from aggressive B-cell lymphoma proliferative B-cell programs. | Blood Cancer Journal

Fig. 2: DEK expression is associated with cell lines derived from aggressive B-cell lymphoma proliferative B-cell programs.

From: DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas

Fig. 2

A DEK log2(TPM + 1) values in B-cell lymphoma/leukemia cell lines. RNA-seq data from the Broad-Novartis Cell Line Encyclopedia was acquired through the DepMap Portal. B Correlation of DEK expression with expression of proliferation markers in cell line RNA-seq data from Fig. 2A. C DEK log2(TPM + 1) values across B-cell development stages. D Western blot of DEK protein expression across B-cell lymphoma cell lines. Bar plot represents DEK expression normalized to β-actin. Representative blot of n = 3 biological replicates, with quantification of all blots shown in the bar plot. Blot has been cropped to display indicated proteins based on molecular weight. E DEK localization in B-cell lymphoma cell line SUDHL6 by confocal microscopy.

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