Fig. 3: Blastoid MCL lymphoma with RAG-mediated CCND1 rearrangement.

A The tumor cells are predominantly medium to large size with round nuclei and blastoid chromatin. Smaller cells with irregular nuclei are also present (H&E stain, original magnification ×400). B Cyclin D1 immunohistochemical staining shows expression in all range of tumor cells (immunoperoxidase, original magnification ×400).