Table 1 Baseline characteristics

From: Plerixafor in poor mobilizers with non-Hodgkin’s lymphoma: a multi-center time-motion analysis

 

Pre-plerixafor era

Plerixafor era

p<

 

(n = 124)

(n = 134)

Age in years

  Mean (SD)

54

(12)

56

(11)

 

  Median (Q1–Q3)

57

(46–63)

58

(49–64)

 

  Range (min–max)

 

(22–73)

 

(20–78)

0.19 (a)

Height in cm

  Mean (SD)

171

(10)

171

(10)

 

  Median (Q1–Q3)

172

(165–178)

171

(164–178)

 

  Range (min–max)

 

(150–204)

 

(143–194)

0.96 (a)

Weight in kg

  Mean (SD)

73

(16)

73

(15)

 

  Median (Q1–Q3)

72

(62–84)

73

(62–82)

 

  Range (min–max)

 

(43–140)

 

(47–118)

0.90 (a)

Months since diagnosis

  Mean (SD)

31

(47)

27

(46)

 

  Median (Q1–Q3)

11

(5–35)

11

(5–30)

 

  Range (min–max)

 

(0–216)

 

(2–270)

0.93 (b)

Gender

  Female—n (%)

49

(40%)

54

(40%)

 

  Male—n (%)

75

(60%)

80

(60%)

0.90 (c)

 Nation

     

  France—n (%)

59

(48%)

63

(47%)

 

  Germany—n (%)

39

(31%)

51

(38%)

 

  Italy—n (%)

26

(21%)

20

(15%)

0.34 (c)

NHL subtype

  Follicular—n (%)

27

(22%)

32

(24%)

 

  Diffuse—n (%)

49

(40%)

54

(40%)

 

  Mantle—n (%)

17

(14%)

18

(13%)

 

  Other—n (%)a

31

(25%)

30

(22%)

0.96 (c)

Disease stage at diagnosis

  I—n (%)

6

(5%)

6

(4%)

 

  II—n (%)

10

(8%)

19

(14%)

 

  III—n (%)

17

(14%)

18

(13%)

 

  IV—n (%)

85

(69%)

87

(65%)

 

  Unknown—n (%)

6

(5%)

4

(3%)

0.58 (c)

Chemotherapy for mobilizationb

  Rituximab—n (%)

6

(5%)

7

(5%)

0.89 (c)

  DHAP/R–DHAP—n (%)

40

(32%)

29

(22%)

0.05 (c)

  ESHAP—n (%)

7

(6%)

2

(1%)

0.09 (d)

  R-CHOP—n (%)

16

(13%)

15

(11%)

0.67 (c)

   Methotrexate—n (%)

3

(2%)

9

(7%)

0.10 (c)

  R–ACVBP—n (%)

3

(2%)

3

(2%)

1.00 (d)

  Other

60

(48%)

86

(64%)

0.01 (c)

Chemotherapy coursesc

  Mean (SD)

1.1

(0.6)

1.2

(0.6)

 

  Median (Q1–Q3)

1

(1–1)

1

(1–1)

 

  Range (min–max)

 

(1–5)

 

(1–5)

0.11 (b)

Chemotherapy daysc

  Ean (SD)

4.1

(5.7)

4.6

(5.5)

 

  Median (Q1–Q3)

3

(1–5)

4

(2–5)

 

  Range (min–max)

 

(1–47)

 

(1–41)

0.02 (b)

  1. (a) Student's t-test, (b) Wilcoxon rank sum, and (c) Chi square (d) Fisher's Exact
  2. a NHL subtypes included in “other” are provided in SI Table 2
  3. b Only chemotherapy regimens given up to 30 days prior to mobilization were considered as part of the mobilization regimen. Each patient received at least 1 chemotherapy regimen. Patients could receive more than 1 chemotherapy regimen
  4. c Chemotherapy courses corresponds to the number of cycles of chemotherapy received prior to apheresis; chemotherapy days corresponds to the number of days chemotherapy was administered