Table 1 Baseline characteristics and therapy of the cohort

From: Chemoimmunotherapy with brentuximab vedotin combined with ifosfamide, gemcitabine, and vinorelbine is highly active in relapsed or refractory classical Hodgkin lymphoma

Characteristics

Entire cohort (n=28)

Male, n (%)

15 (53%)

Age at HCT, median (range)

25 (15–49)

Stage at Dx, n (%)

  II

7 (25)

  III

6 (21)

  IV

15 (54)

Constitutional Symptoms at Dx, n (%)

20 (71)

Bulky Disease at Dx, n (%)

8 (29)

Front Line Treatment, n (%)

  ABVD

23 (82)

  ABVD → EscBEACOPP

4 (14)

  Other

1 (4)

IFRT, n (%)

5 (18)

Refractory (≤ 3 months remission), n (%)

12 (43)

Time to relapse, median months (range)

7.9 (1.9–133)

IGEV-Bv order of salvage, n (%)

  First

14 (50)

  Subsequent

14 (50)

No. of salvage cycles, median (range)

2 (2–6)

Number of cycles at stem cell collection, median (range)

2 (1–5)

Days of collection, median (range)

1 (1–2)

CD34x106/kg collected, median (range)

13.6 (2.8–44.8)

PET/CT status post IGEV-Bv, n (%)

  Complete metabolic response

20 (71)

  Partial metabolic response

7 (25)

  Stable disease

1 (4)

 Median follow-up, months (range)

17 (0–65)

  1. HCT hematopoietic stem cell transplant, Dx diagnosis, PET/CT positron emission tomography/computed tomography, ABVD doxorubicin, bleomycin, vinblastine, and dacarbazine, escBEACOPP escalated bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone, IFRT involved field radiotherapy, IGEV-Bv ifosfamide, gemcitabine, and vinorelbine with brentuximab vedotin