Fig. 1: Diagnostic workup for case 1 and 2. | Bone Marrow Transplantation

Fig. 1: Diagnostic workup for case 1 and 2.

From: COVID-19 in allogeneic stem cell transplant: high false-negative probability and role of CRISPR and convalescent plasma

Fig. 1

a Transverse CT scan showing lung infiltrates suspicious for COVID-19 disease for case 1. b CRISPR analysis testing for the presence of the viral genome in the shown sample of case 1. We used genomic RNA extracted from heat-inactivated SARS-CoV-2 (NR-52347, BEI) as positive control, and human RNA isolated from HEK293T cells as negative control. Each experiment was run in triplicate. Values that are 3 SD above the negative control mean were considered positive. The level of fluorescence does not reflect viral load, this is a qualitative test. c CRISPR analysis testing for the presence of the viral genome in the shown sample of case 2 tested as in b.

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