Table 1 Baseline characteristics of patients and controls.

From: Ocular surface indicators and biomarkers in chronic ocular graft-versus-host disease: a prospective cohort study

 

Characteristic

Intended HSCT cohort (n = 40)a

Controls (n = 20)a

Age

Median (range)

40.5 (20–70)

38.5 (21–73)

Mean

41.3

39.3

Sex

Male

21 (52.5%)

9/20 (45.0%)

Female

19 (47.5%)

11/20 (55.0%)

Primary diagnosis

AA

8 (20%)

 

ALL

9 (22.5%)

 

AML

7 (17.5%)

 

APL

1 (2.5%)

 

CGD

1 (2.5%)

 

CLL

1 (2.5%)

 

Cutaneous Lymphoma

1 (2.5%)

 

Follicular Lymphoma

1 (2.5%)

 

HL

1 (2.5%)

 

Mantle Cell Lymphoma

1 (2.5%)

 

MDS

4 (10.0%)

 

MM

1 (2.5%)

 

Plasmocytic dendritic cell neoplasm

1 (2.5%)

 

SCA

3 (7.5%)

 

Type of transplant (n = 36)b

HLA matched

32 (88.8%)

 

Unmatched

4 (11.1%)

 

Total Body Irradiation

Yes

25 (69.4%)

 

Low-dose (<600 Gy)

6/25 (24.0%)

 

High-dose (≥600 Gy)

19/25 (76.0%)

 

No

11 (30.5%)

 

Conditioning regimen

Myeloablative

20 (55.5%)

 

Non-Myeloablative

16 (44.4%)

 

SteM cell source

Cord blood and peripheral blood

4 (11.1%)

 

Peripheral blood

32 (88.8%)

 
  1. aN corresponds to the number of participants.
  2. bFour patients did not receive an HSCT.
  3. HSCT hematopoietic stem cell transplant, AA aplastic anemia, ALL acute lymphoblastic leukemia, AML acute myeloid leukemia, APL acute promyelocytic anemia, CGD chronic granulomatous disease, CLL chronic lymphoblastic leukemia, HL hodgkin lymphoma, MDS myelodysplastic syndrome, MM multiple myeloma, SCA sickle cell anemia, HLA human leukocyte antigen, Gy gray.