Table 5 Ocular GVHD cohort: comparison of ocular surface indicators at time of diagnosis vs. baseline.

From: Ocular surface indicators and biomarkers in chronic ocular graft-versus-host disease: a prospective cohort study

 

Na

oGVHD at Baseline

oGVHD at Diagnosis

Wilcoxon p value

Median (Range)

Median (Range)

Ocular surface parameters

OSDI

10

2.1 (0.0, 12.5)

2.5 (0.0, 44.0)

0.47

Oxford Corneal Staining Score

23

1.8 (0.1, 5.1)

4.6 (0.4, 9.8)

0.0001

Schirmer’s Test (mm)

23

10.0 (3.0, 25.0)

3.0 (0.0, 10.0)

<0.0001

Tear Osmolarity (mOsm/L)

23

308.0 (296.0, 345.0)

309.0 (288.0, 343.0)

0.86

TBUT (s)

23

9.0 (2.7, 13.0)

4.7 (2.3, 9.7)

0.0004

  1. aN corresponds to the number of participants for OSDI; otherwise, corresponds to number of eyes.
  2. OSDI ocular surface disease index, TBUT tear break-up time.
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