Table 1 Patient characteristics in the entire cohort (first column) and according to the hematopoietic cell transplantation comorbidity index (HCT-CI). Absolute numbers and percentages are given.
Variable | Overall (n = 38760) | HCT-CI = 0 (n = 22699) | HCT-CI = 1 or 2 (n = 8101) | HCT-CI ≥ 3 (n = 7558) | |
|---|---|---|---|---|---|
Donor cell source | Bone marrow | 3358 (8.7%) | 2134 (9.4) | 639 (7.9) | 550 (7.3%) |
Peripheral blood | 35402 (91.3%) | 20565 (90.6) | 7462 (92.1%) | 7008 (92.7%) | |
Diagnosis | Acute leukemia | 22991 (59.3%) | 13417 (59.1) | 4825 (59.6%) | 4509 (59.7%) |
Chronic leukemia | 2427 (6.3%) | 1596 (7.0) | 461 (5.7%) | 344 (4.6%) | |
Lymphoma | 5070 (13.1%) | 3199 (14.1) | 981 (12.1%) | 857 (11.3%) | |
MDS/MPN | 8272 (21.3%) | 4487 (19.8) | 1834 (22.6%) | 1848 (24.5%) | |
Complete remission at transplant | Yes | 23791 (61.4%) | 14293 (63.0) | 4908 (60.6%) | 4376 (57.9%) |
No | 14969 (38.6%) | 8406 (37.0) | 3193 (39.4%) | 3182 (42.1%) | |
Patient age (years) | Median (min–max) [IQR] | 53.3 (18–83.8) [41.1–61.5] | 51.1 (18–79.7) [38.2–60.2] | 54.8 (18–83.8) [44–62.3] | 56.9 (18–78.6) [46.8–63.6] |
Patient sex | Male | 22896 (59.1%) | 13536 (59.6) | 4922 (60.8%) | 4192 (55.5%) |
Female | 15864 (40.9%) | 9163 (40.4) | 3179 (39.2%) | 3366 (44.5%) | |
Intensity of conditioning | Reduced-intensity | 20147 (52%) | 10653 (46.9) | 4492 (55.4%) | 4747 (62.8%) |
Myeloablative | 18613 (48%) | 12046 (53.1) | 3609 (44.6%) | 2811 (37.2%) | |
Conditioning contains | Yes | 8976 (23.2%) | 5326 (23.5) | 1863 (23%) | 1700 (22.5%) |
Total body irradiation | No | 29784 (76.8%) | 17373 (76.5) | 6238 (77%) | 5858 (77.5%) |
In vivo T-cell depletion | Yes | 24852 (64.4%) | 14321 (63.4) | 5278 (65.4%) | 4957 (65.9%) |
No | 13724 (35.6%) | 8255 (36.6) | 2795 (34.6%) | 2570 (34.1%) | |
missing | 184 | 123 | 28 | 31 |
