Table 2 Multivariate cox regression for overall survival.

From: Impact of chronic graft-versus-host-disease on intensive care outcome in allogeneic hematopoietic stem cell recipients

Risk factor

HR

CI 95%

P value

HLA mismatch

1.40

0.86–2.29

0.178

Time from HSCT to ICU admission (during/after 1st year of HSCT)

1.56

1.03–2.39

0.035

GI cGvHD

1.40

0.87–2.72

0.160

cGvHD of other subtypes

0.84

0.52–1.35

0.469

Overlap subtype of cGvHD

1.26

0.68–2.33

0.460

Need for RRT

1.73

1.14–2.62

0.010

Need for ECLA (ECCO2R/vvECMO/vaECMO: yes/no)

1.54

0.87–2.72

0.137

Need for IMV

1.08

1.02–1.14

0.007

Need for vasopressors during first 24h

0.97

0.89–1.06

0.543

  1. cGvHD chronic Graft-vs-Host Disease, ECLA extracorporeal life assist, GI gastrointestinal, HR hazard ratio, HSCT allogeneic stem cell transplantation, ICU intensive care unit, IMV invasive mechanical ventilation, RRT renal replacement therapy.
  2. The bold values mark the risk factors with a p value below the significance level of 0.05.
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