Table 3 Key Questions in the field of TCR sequencing in GvHD.
From: Potential of TCR sequencing in graft-versus-host disease
Key Questions: |
|---|
Potential clinical applications of TCR sequencing in GvHD |
∙ Does TCR diversity predict the probability of GvHD? |
∙ Does TCR diversity during GvHD predict outcome and/or therapy response? |
∙ Does GvHD directly impact subsequent TCR diversity and does this impact outcome? |
∙ Are common clonotypes shared among individuals with GvHD? |
