Table 1 Baseline patient and donor characterisitcs.
Patient and donor characteristics | |
|---|---|
Variable | N = 299 (%) |
Patient age | |
Age <46 | 106 (35.5) |
Age 46–65 | 138 (46.2) |
Age >65 | 55 (18.4) |
Median (Standard deviation) | 56 (15.7) |
Diagnosis* | |
AML | 196 (65.6) |
ALL | 40 (13.4) |
MDS/MPN | 38 (12.7) |
Other | 25 (8.4) |
Disease Risk Index | |
Low | 34 (11.4) |
Intermediate | 120 (40.1) |
High/Very high | 145 (48.5) |
HCT Comorbidity Index** | |
0–2 | 79 (26.4) |
3 or greater | 220 (73.6) |
Disease status at transplant | |
Active | 110 (36.8) |
Remission | 189 (63.2) |
Conditioning | |
Myeloablative | 152 (50.8) |
Non-myeloablative | 147 (49.2) |
Karnofsky performance status*** | |
<80 | 48 (16.1) |
80 or greater | 250 (83.9) |
Donor age | |
<30 | 76 (25.4) |
30–44 | 105 (35.1) |
>44 | 118 (39.5) |
Median (Standard deviation) | 38 (14.2) |
Donor sex | |
Female | 108 (36.1) |
Male | 191 (63.9) |
Relationship category | |
Child | 137 (45.8) |
Parent | 35 (11.7) |
Sibling | 110 (36.8) |
Other | 17 (5.7) |
ABO mismatch | |
Major | 5 (1.7) |
Minor | 4 (1.3) |
CMV¶ match status | |
Donor+/recipient+ | 99 (33.8) |
Donor+/recipient- | 39 (13.3) |
Donor-/recipient+ | 79 (27.0) |
Donor-/recipient- | 76 (25.9) |
HLA§ match grade | |
5/10 | 184 (61.5) |
>5/10 | 115 (38.5) |
HLA§ DRB1 match | |
Yes | 34 (11.4) |
