Table 4 Univariate analysis of acute and chronic GvHD occurence.
Variable | Modality | Total | Day + 100 aGvHD grade II–IV | Day + 100 aGvHD grade III–IV | 6 y cGvHD | 6 y ext cGvHD |
|---|---|---|---|---|---|---|
Year of HCT | [2000–2007] | 16 (45.7) | 50 [23.4–71.8] | 12.5 [1.9–33.6] | 12.5 [1.7–34.4] | 8.3 [0.4–33.3] |
[2008–2022] | 19 (54.3) | 29.4 [10.1–52] | 5.9 [0.3–24.3] | 20 [4.3–43.9] | 20 [4.3–43.9] | |
P value | 0.25 | 0.49 | 0.46 | 0.21 | ||
Age at HCT (years) | (0–6) | 19 (54.3) | 41.2 [17.7–63.4] | 0 | 14.7 [2.1–38.7] | 10.5 [0.4–39.3] |
[6–18) | 16 (45.7) | 37.5 [14.6–60.7] | 18.8 [4.3–41.1] | 18.8 [4.2–41.3] | 18.8 [4.2–41.3] | |
P value | 0.84 | 0.07 | 0.61 | 0.3 | ||
Recipient sex | Male | 23 (65.7) | 38.1 [17.7–58.4] | 9.5 [1.5–26.7] | 16.9 [3.7–38.4] | 11.9 [1.6–33] |
Female | 12 (34.3) | 41.7 [14–67.7] | 8.3 [0.4–32.3] | 16.7 [2.3–42.6] | 16.7 [2.3–42.6] | |
P value | 0.9 | 0.88 | 0.92 | 0.53 | ||
Donor type | MSD | 17 (48.6) | 18.8 [4.3–41.1] | 0 | 13.4 [2–35.8] | 6.7 [0.4–27.1] |
non-MSD | 18 (51.4) | 58.8 [31–78.6] | 17.6 [4.1–39] | 20.4 [4.3–44.8] | 21.9 [4.4–47.8] | |
P value | 0.01 | 0.08 | 0.65 | 0.35 | ||
Source of HCs | BM | 15 (42.9) | 42.9 [16.6–67] | 7.1 [0.4–28.5] | 22.1 [4.8–47.1] | 14.3 [2.1–37.5] |
other | 20 (57.1) | 36.8 [15.9–58.2] | 10.5 [1.7–29.1] | 12.3 [1.8–33.7] | 13.3 [1.8–36.3] | |
P value | 6 (17.1) | 0.88 | 0.72 | 0.39 | 0.66 |
