Table 5 Non-relapse mortality—patient and transplant characteristics, and causes.

From: Outcomes of allogeneic haematopoietic cell transplantation for myelofibrosis in children and adolescents: the retrospective study of the EBMT Paediatric Diseases WP

Age at HCT

Year of HCT

MF status at HCT

Donor type

Source of HCs

Conditioning regimen

Ex vivo TCD

In vivo TCD

GVHD prophylaxis

Survival (days after HCT)

Cause of death

17.4

2011

PMF

MSD

PB

Cy+Flu

No

ATG

CSA + MTX

13

Graft failure

1.7

2013

PMF

UD 5/6

CB

Treo+Flu+Thio

No

ATG

CSA + MMF

32

Graft failure

4.7

2003

PMF

MSD

PB

Bu+Cy

No

NA

missing

644

Graft failure

11.7

2000

PMF

UDa

PB

TBI alone

Yes

NA

missing

62

acute GvHD

17.6

2005

PMF

UD 10/10

PB

Bu+Cy+Flu

Yes

No

CSA + MTX

102

acute GvHD

14.9

2007

PMF

UD (2/6; 3/6)

CB-double

Bu+Cy

No

No

CSA

109

acute GvHD

  1. aHLA not reported.
  2. HCT haematopoietic cell transplantation, MF myelofibrosis, PMF primary myelofibrosis, HCs haematopoetic cells, MSD matched sibling donor, UD unrelated donor, PB peripheral blood, CB cord blood, Cy cyclophosphamide, Flu fludarabine, Treo treosulfan, Thio thiothepa, Bu busulfan, TBI total body irradiation, TCD T-cell depletion, GvHD graft versus host disease, ATG anti-thymocyte globuline, CSA cyclosporine A, MTX methotrexate, MFF mycophenolate mofetil.