Table 2 Univariate analysis.
Univariate analysis | 3 y GRFS | 3 y NRM | 3 y REL | 3 y OS | 3 y LFS |
|---|---|---|---|---|---|
p | p | p | p | p | |
SCT year | 0.4 | 0.85 | 0.15 | 0.6 | 0.3 |
SCTyear ≤2014 | 42% | 20% | 16% | 64% | 58% |
SCTyear > 2014 | 36% | 21% | 10% | 65% | 69% |
ATLG vs PTCY | 0.22 | 0.86 | 0.4 | 0.9 | 0.54 |
ATLG | 43% | 20% | 19% | 65% | 60% |
PTCY | 34% | 21% | 12% | 64% | 67% |
Match vs Mismatch | 0.9 | 0.55 | 0.64 | 0.39 | 0.4 |
Match | 38% | 19% | 13% | 68% | 65% |
Mismatch | 39% | 22% | 14% | 60% | 59% |
Patient/Donor SEX | 0.9 | 0.31 | 0.46 | 0.38 | 0.36 |
M/M | 39% | 19% | 19% | 63% | 60% |
M/F | 35% | 31% | 5% | 64% | 58% |
F/F | 35% | 25% | 17% | 58% | 58% |
F/M | 43% | 12% | 6% | 81% | 74% |
Patient/Donor CMV | 0.3 | 0.9 | 0.05 | 0.021 | 0.08 |
neg/neg | 44% | 20% | 5% | 77% | 71% |
neg/pos | 49% | 21% | 0% | 79% | 72% |
pos/pos | 36% | 18% | 17% | 64% | 63% |
pos/neg | 25% | 24% | 30% | 36% | 36% |
ABO incompatibility | 0.47 | 0.47 | 0.18 | 0.69 | 0.67 |
Compatible | 39% | 24% | 9% | 67% | 65% |
Minor incomp. | 41% | 20% | 20% | 62% | 60% |
Major incomp. | 46% | 14% | 11% | 70% | 67% |
bidirectional incomp. | 20% | 13% | 27% | 53% | 53% |
Patient age | 0.032 | 0.03 | 0.99 | 0.021 | 0.041 |
≤36 | 49% | 13% | 13% | 74% | 72% |
>36 | 28% | 28% | 15% | 54% | 53% |
Donor age | 0.33 | 0.87 | 0.09 | 0.28 | 0.29 |
≤37 | 37% | 19% | 19% | 64% | 61% |
>37 | 40% | 22% | 8% | 66% | 65% |
Stemcell source | 0.9 | 0.5 | 0.03 | 0.03 | 0.018 |
BM | 40% | 25% | 25% | 50% | 47% |
PBSC | 38% | 19% | 10% | 70% | 68% |
CD34 infused cells | 0.88 | 0.14 | 0.45 | 0.05 | 0.049 |
≤6.7 | 38% | 26% | 15% | 56% | 53% |
>6.7 | 39% | 14% | 12% | 75% | 72% |
B-ALL vs T-ALL | 0.97 | 0.59 | 0.69 | 0.6 | 0.81 |
B-ALL | 38% | 21% | 13% | 63% | 62% |
T-ALL | 41% | 17% | 15% | 70% | 65% |
BCR-ABL | 0.54 | 0.89 | 0.49 | 0.89 | 0.7 |
Neg | 31% | 24% | 12% | 60% | 59% |
Pos | 37% | 22% | 13% | 64% | 60% |
MRD | 0.8 | 0.33 | 0.77 | 0.37 | 0.4 |
Neg | 39% | 20% | 9% | 69% | 69% |
Pos | 36% | 14% | 11% | 74% | 70% |
Conditioning | 0.43 | 0.65 | 0.17 | 0.5 | 0.24 |
TBICyVP16 | 44% | 23% | 17% | 62% | 54% |
TBICy | 41% | 14% | 9% | 73% | 73% |
TBIFlu | 34% | 21% | 12% | 64% | 60% |
TBI dose | 0.32 | 0.61 | 0.02 | 0.22 | 0.23 |
<12 Gy | 28% | 18% | 31% | 50% | 50% |
12 Gy | 40% | 21% | 10% | 68% | 65% |
