Fig. 1: Clinical outcomes by FLT3-TKD MRD status.

Rates of (a) relapse and (b) overall survival for patients based on the presence (MRDpos) or absence (MRDneg) of residual FLT3 tyrosine kinase domain (TKD) variants in pre-transplant blood. FLT3-TKD MRDpos patients were divided by the level of residual disease based on variant allele fraction (VAF) above or below 0.1%. Survival curves plotted using the Kaplan-Meier estimator and compared with the log-rank test and cumulative incidence of relapse plotted using the cumulative incidence function and compared with Gray’s test.