Table 3 Immune reconstitution of patients after SCT for β-Thalassemia.

From: αß T-cell depleted haploidentical stem cell transplantation for pediatric and young adult patients with transfusion-dependent thalassemia

T-and B cell recovery

MSD

T-haplo-HSCT

TCRα/β/CD19

CD3/CD19

CD3+ T cells > 0.5 ×109 L−1

137 (32–211)

192 (110–229)

201 (138–229)

173 (110–227)

CD4+ T cells > 0.2 ×109 L−1

130 (39–211)

180 (96–306)a

176 (96–188)a

181 (110–306)

CD8+ T cells > 0.2 ×109 L−1

41 (32–166)

167 (75–246)

174 (127–246)

110 (75–227)

CD19+ B cells > 0.1 ×109 L−1

62 (46–89)

47 (40–224)

47 (40–146)

110 (40–227)

  1. Median (minimum-maximum) values are shown as days after SCT and percentages, respectively; T-haplo-HSCT indicates patients who underwent T-haplo-HSCT (both T-cell depletion procedures), CD3/CD19 patients only with CD3/CD19 T-cell depletion, TCRαβ/CD19 patients only with TCRαβ/CD19 T-cell depletion, MSD patients with HLA identical donor (matched sibling donor).
  2. aOne value missing as patient has not yet reached necessary cell count.
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