Table 1 Patients donors and transplant characteristics.
FLAMSA-FB | Standard | p | |
|---|---|---|---|
N (%) | N (%) | ||
Number of patients | 45 (100) | 61 (100) | |
Patient age median (range) | 56 (20–72) | 62 (28–77) | 0.024 |
Patient sex | 0.693 | ||
Male | 34 (76) | 44 (72) | |
Female | 11 (24) | 17 (28) | |
Patient CMV serology | 0.56 | ||
Neg | 21 (47) | 25 (41) | |
Pos | 24 (53) | 36 (59) | |
ECOG | 0.259 | ||
0 | 17 (50) | 19 (33) | |
1 | 15 (44) | 35 (60) | |
2 | 2 (6) | 4 (7) | |
Donor age median (range) | 34 (18–63) | 32 (20–66) | 0.74 |
Donor sex | 0.136 | ||
Male | 35 (78) | 54 (89) | |
Female | 10 (22) | 7 (12) | |
Donor CMV serology | 0.297 | ||
Neg | 19 (42) | 32 (53) | |
Pos | 26 (58) | 29 (47) | |
IPSS | 0.162 | ||
Low | 3 (7) | 9 (16) | |
Intermediate 1 | 6 (14) | 14 (26) | |
Intermediate 2 | 28 (64) | 22 (41) | |
High | 7 (16) | 9 (17) | |
BM blasts at SCT median (range) | 12 (5–19) | 8 (5–19) | 0.007 |
SCT year median(range) | 2010 (2006–2020) | 2021 (2000–2024) | <0.001 |
Type of allo-SCT | 0.426 | ||
MRD | 9 (20) | 10 (16) | |
Haplo | 1 (2) | 6 (10) | |
MUD | 23 (51) | 32 (53) | |
MMUD | 12 (27) | 13 (21) | |
MACRIC | 0.144 | ||
MAC | 9 (20) | 20 (33) | |
RIC | 36 (80) | 41 (67) | |
Conditioning | <0.001 | ||
FLAMSA BuFlu | 45 (100) | 0 (0) | |
TreoFlu | 0 (0) | 15 (25) | |
BuFlu | 0 (0) | 16 (26) | |
BuTT | 0 (0) | 30 (49) | |
ATG/ATLG | 0.54 | ||
No ATG/ATLG | 7 (16) | 7 (12) | |
ATG/ATLG | 38 (84) | 54 (89) | |
Type | <0.001 | ||
ATLG | 23 (61) | 53 (98) | |
Thymoglobulin | 15 (40) | 1 (2) | |
PTCY | 0.019 | ||
No PTCY | 45 (100) | 54 (89) | |
PTCY | 0 (0) | 7 (11) | |
CD34 x 10 x 6 kg median (range) | 7 (2–14) | 7 (2–19) | 0.63 |
