Fig. 4
From: Advanced smart biomaterials and constructs for hard tissue engineering and regeneration

Smart dental composites for caries inhibition. a Composites with calcium (Ca) ion release. The phosphate (P) ion release had a similar trend. Ion release substantially increased at a cariogenic pH 4 when these ions were most needed to combat caries. There was little release at a neutral pH to preserve the ion reservoir. b Remineralization. Dentin lesions without composite had substantial mineral loss. Dentin lesions restored with commercial composite had little remineralization. The smart composites caused successful remineralization. (Adapted from ref. 128, with permission.)