Fig. 5
From: Advanced smart biomaterials and constructs for hard tissue engineering and regeneration

Effect of smart resins on neutralizing biofilm acids and increasing the pH to avoid tooth decay. The adhesive resin contained MPC, DMAHDM and NACP from 0 to 40%. A dental plaque microcosm biofilm model was used with human saliva as inoculum. The pH of the biofilm medium with resin that contained 30 and 40% NACP was at pH 6 or greater. The pH of the biofilm medium with commercial adhesive was cariogenic at approximately pH 4, which could demineralize the tooth structures. (Adapted from ref. 132, with permission.)